In humans, the tailbone, also known as the coccyx, is a small triangular bone located at the base of the spine. It is made up of three to five fused (joined together) vertebrae and is the remnant of a tail that our evolutionary ancestors used for balance and communication. The coccyx is not attached to the colon; rather, it is a part of the vertebral column and provides support for the pelvic organs.

Cholera, caused by the bacterium Vibrio cholerae, can be both epidemic and endemic. Epidemic cholera refers to sudden outbreaks affecting large populations, often due to contaminated water. Endemic cholera signifies the continuous, stable presence of the disease in specific regions, indicating a persistent, albeit lower, level of infection over time.