The Inter-Services Intelligence (ISI) is the premier intelligence agency of Pakistan, responsible for providing critical national security and intelligence assessments to the government. It was established in 1948 and operates under the jurisdiction of the Pakistan Ministry of Defence. The ISI is primarily focused on safeguarding Pakistan's interests, both domestically and internationally, and plays a crucial role in counterintelligence, counterterrorism, and strategic intelligence.

Mount Everest, the highest peak in the world, is named after Sir George Everest, a Welsh geographer and surveyor general of India in the 19th century. Although Sir George Everest himself objected to having the mountain named after him, the proposal was accepted, and the mountain retained the name Everest. The naming was done by the Royal Geographical Society in 1865 to honor his contributions to the Great Trigonometrical Survey of India, which played a significant role in mapping the subcontinent.

Syria's capital, Damascus, is the oldest capital in existence. It is the fourth holiest city in Islam, according to some. Damascus was established in the third millennium B.C., making it one of the Middle East's oldest cities.

The San Francisco Conference, officially known as the United Nations Conference on International Organization, took place from April 25 to June 26, 1945. Therefore, the correct answer is:

(D) 25 April 1945